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In nerves uncovered to 100 Hz when bathed in 10 mM glucose, Healthy Flow Blood USA the CAP failed suggesting that even within the presence of normoglycemic glucose extra energy substrate is required when the tissue energy demand increases. Such data are vital as they show that glycogen has an essential function underneath physiological circumstances. The fact that glycogen supported CAP conduction within the absence of exogenously applied glucose probably has no value in ascribing a role to glycogen, since aglycaemia is an synthetic experimental process, and hypoglycemia is an iatrogenic consequence of insulin therapy that didn't exist prior to 1922 (Frier et al., 2014), thus can't be glycogen’s essential role. However supplying lactate to axons when tissue power demand Healthy Flow Blood USA increases implies a novel position for brain glycogen and suggests it acts as an energy buffer moderately than an vitality reserve, whose position is not to single-handedly support conduction, but to act in concert with ambient levels of normoglycemic glucose.

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